diff --git a/regint.h b/regint.h
index 5543ca8..c389477 100644
--- a/regint.h
+++ b/regint.h
@@ -50,6 +50,7 @@

 #if defined(__i386) || defined(__i386__) || defined(_M_IX86) || \
     defined(__x86_64) || defined(__x86_64__) || defined(_M_AMD64) || \
+    defined(__powerpc64__) || \
     defined(__mc68020__)
 #define PLATFORM_UNALIGNED_WORD_ACCESS
 #endif
diff --git a/siphash.c b/siphash.c
index cd8ba62..0df96f8 100644
--- a/siphash.c
+++ b/siphash.c
@@ -30,6 +30,7 @@
 #ifndef UNALIGNED_WORD_ACCESS
 # if defined(__i386) || defined(__i386__) || defined(_M_IX86) || \
      defined(__x86_64) || defined(__x86_64__) || defined(_M_AMD64) || \
+     defined(__powerpc64__) || \
      defined(__mc68020__)
 #   define UNALIGNED_WORD_ACCESS 1
 # endif
diff --git a/st.c b/st.c
index 3bb85c2..9f21a96 100644
--- a/st.c
+++ b/st.c
@@ -1320,6 +1320,7 @@ strhash(st_data_t arg)
 #ifndef UNALIGNED_WORD_ACCESS
 # if defined(__i386) || defined(__i386__) || defined(_M_IX86) || \
      defined(__x86_64) || defined(__x86_64__) || defined(_M_AMD64) || \
+     defined(__powerpc64__) || \
      defined(__mc68020__)
 #   define UNALIGNED_WORD_ACCESS 1
 # endif